Kamokamotihan

Family • Convolvulaceae - Ipomoea hederacea (Linn.) Jacg. - IVY-LEAF MORNING GLORY - La ba hua

Scientific names

Convolvulus hederaceus Linn.
Convolvulus nil Linn.
Ipomoea nil Roth.
Ipomoea hederacea (Linn.) Jacq.
Ipomoea barbigera Sweet
Pharbitis hederacea Choisy

Common names

Bulakan (Tag.)
Kamokamotihan (Tag.)
Kaladanae (Hindus.)
Ivy-leaf morning glory (Engl.)

Other vernacular names

CHINESE: La ba hua, Qian hiu hua.

Kamokamotihan

Botany
Kamokamotihan is a twining, rather slender, herbaceous, more or less hairy, annual vine reaching a length of several meters. Leaves are prominently 3-lobed, subovate, 8 to 15 centimeters long, heart-shaped at the base. Peduncles are solitary, shorter than the petioles, borne in the axils of leaves, each with 1 to 6 flowers. Calyx is green, very hairy at the base, and about 3 centimeters long. Corolla is pale blue, or the tube white within, turning purplish pink, about 5 centimeters long, with the limb shallowly 5-lobed. The capsules are ovoid, about 1 centimeter diameter, each containing 2 black and smooth seeds.

Additional Sources and Suggested Readings

(1) Poly(acrylonitrile) Grafted Ipomoea Seed-Gums: A Renewable Reservoir to Industrial Gums / Vandana Singh et al / Biomacromolecules, 2005, 6 (1), pp 453–456 / DOI: 10.1021/bm049518b

(2) HEPATOPROTECTIVITY AND AN ANTIOXIDANT STUDY OF IPOMOEA HEDERACEA ON EXPERIMENTALLY INDUCED HEPATOTOXIC RATS / Ruckmani Devi S, M. Chitra and P. Jayamathi / Recent Research in Science and Technology 2010, 2(11): 17-19

(3) Ipomoea hederacea: an Imperative Source for Natural Antioxidants / Aziz-ur-Rehmana, Ansur Abbas, Tauheeda Riaz, Shargeel Ahmad et al / Asian Journal of Pharmaceutical and Biological Research

(4) NEMATICIDAL ACTIVITY OF SELECTED FLORA OF PAKISTAN / MUHAMMAD ZIA UL HAQ, MANSOOR AHMAD AND MUSSARAT AKHTER / Pak. J. Bot., 42(3): 2119-2123, 2010.

(5) ANTIMICROBIAL SCREENING OF SELECTED FLORA OF PAKISTAN / M. Zia-Ul-Haq et al / Arch. Biol. Sci., Belgrade, 63 (3), 691-695, 2011 DOI:10.2298/ABS1103691Z

(6) Chemical Investigation of Seed of Ipomoea hederacea and its Biological Activity / B. P. Singh and Sandhya Singh / Journal of Chemical and Pharmaceutical Research, 2012, 4(2):1441-1448

(7) Chemical Investigation of Seed of Ipomoea hederacea and its Biological Activity / B. P. Singh* and Sandhya Singh / Journal of Chemical and Pharmaceutical Research, 2012, 4(2):1441-1448

(8) Compositional study and antioxidant potential of Ipomoea hederacea Jacq. and Lepidium sativum L. seeds. / Zia-Ul-Haq M, Ahmad S, Calani L, Mazzeo T, Del Rio D, Pellegrini N, De Feo V. / Molecules. 2012 Aug29; 17(9):10306-21. doi: 10.3390/molecules170910306.

Kamokamotihan2

Distribution
– Found in Abra, Lepanto, Bontoc, and Rizal Provinces in Luzon, In thickets and waste places at low and medium altitudes.
– Some forms cultivated for their flowers.
– Native of tropical America, but pantropic in distribution.

Kamokamotihan3

Constituents
• The active principle is the kalandana resin, called “Pharbitisin” in India. It is considered comparable to the resin of jalap or the convolvulin from Ipomoea purga.
• Phytochemical studies of various fractions yielded reducing sugars, alkaloids, terpenoids, saponins, flavonoids, and tannins.
• Compositional analysis of seeds yielded oil (14.09), fiver (16.55). Major fatty acids were oleic acid and linoleic acid.

Properties
• Resin has a nauseous and acrid taste with an unpleasant odor, especially when heated.
• Seeds considered cathartic, analgesic, antiseptic.

Part utilized
Seeds

Kamokamotihan5

Uses
Folkloric
– No reported folkloric medicinal use in the Philippines.
– In India, besides the resin, the pharmacopoeia includes an extract, tincture and compound powder.
– In many parts of India, roasted seeds are used as purgative; the powdered seeds used for constipation.
– In China, seeds are used as diuretic, antihelmintic, deobstruent; prescribed for constipation and dropsy, also to promote menstruation and as an abortifacient.

Kamokamotihan4

Study Findings
• Phytochemicals: Study isolated five ecdysteroids (hederasterone A, hederasterone A-20,22 monoacetonide and hederasterone B) , two steroidal glycosides, one triterpene and two aromatic acids.One compound showed inhibition of butyrylcholinesterase, another inhibited lypooxygenase.
• Hepatoprotective / Antioxidant: Ethanol extract of Ipomoea hederacea was shown to have hepatoprotective and antioxidant potential against carbon tetrachloride induced hepatotoxicity in rats.
• Antioxidant: Study of an ethyl acetate fraction yielded the highest phenolic content and highest antioxidant activity compared to other fractions.
• Nematicidal: Study evaluated the potential toxicity of selected medicinal plants against juveniles of the root-knot nematode Meloidogyne spp and Cephalobus litoralis. Ipomoea hederacea exhibited moderate activity.
• Antibacterial: In a study screening the antimicrobial activity of selected flora of Pakistan, Ipomoea heredacea showed highest activity against Bacillus subtilis and highest activity against the fungal strains.
• Seeds / Antibacterial: Various seed extracts were studied for antibacterial activity. The methanol extract was found to be more active than other extracts against E. coli, Pseudomonas aeruginosa and fungi. Chemical constituents like saponins and alkaloids were probably responsible for the antimicrobial activity of the crude drug.
• Toxicity Study/ Analgesic: Mice study evaluating the toxic and non-toxic profile of Ipomoea hederacea showed a starting lethal dose of 300 mg/kg with a calculated LD50 value of 229.2 mg/kg dose. Dose-dependent toxic behavior included convulsion, tremor, unsteady gait, respiratory distress to death. Hot plate analgesic activity exhibited analgesic potential.
• Seeds / Antimicrobial: A methanol extract of seed exhibited varying levels of antibacterial activity against E coli and Pseudomonas aeruginosa. Methanol and chloroform extracts showed moderate activity against Alternaria brassica, A. braceacola, and Aspergillus niger fungal strains.

Availability
Wild-crafted.
Seeds in the cybermarket.