Pakuan

Family • Cucurbitaceae - Citrullus vulgaris Schrad. - WATERMELON - Han gua

Scientific names

Curcubita citrullus Linn.
Citrullus edulis Spach
Citrullus lanatus (Thunb.) Matsum. & Nakai
Citrullus vulgaris Schrad.
Momordica lanata Thunb.
Xi gua (Chin.)

Common names

Pakuan (Tag.)
Sandia (Span.)
Timun (Sul.)
Watermelon (Engl.)
Han gua (Chin.)

Other vernacular names

AFRIKAANS: Waatlemoen. GREEK : Kαρπούζι Karpusi, Karpouzia (Cyprus).
ARABIC : Battikh (baṭṭīḫ), Battikh ahmar (red-fleshed), Bateekh, Betteakh (Egypt). HEBREW : Avatiach, Avatiach pashut.
BENGALI : Taramuj, Tormuj. HINDI : Kharbuza ( kharmuja), Tarabūja, Tarabuuza.
BULGARIAN : Dinia. ITALIAN : Anguria, Cocomero (Tuscany), Melone d’acqua, Pastecca.
CATALAN : Sindriera. KOREAN : Su bak (Soo bahk).
CHINESE : Shi yong xi gua, Choei koa, Ts’ing teng koa, Han koa, Hia koa. LAOTIAN : Môô, Tèèng môô.
CROATIAN : Lubenica. NEPALESE : Tarabuujaa (Tarbuja).
CZECH : Cukrový meloun, Lubenice meloun, Lubenice obecná, Meloun vodní, Vodní meloun. PORTUGUESE: Melancia, Melância.
DANISH : Vandmelon. SPANISH : Sandía, Melón de agua.
DUTCH : Watermeloen. SWAHILI : Mtango, Mtikiti.
ESTONIAN : Arbuus, Vesimelon. TAMIL : Palam, Vattākku.
FRENCH : Melon d’eau, Pastèque. THAI : Taeng chin, Taeng moh, Matao.
GERMAN: Wassemelone, Wassermelone , Gewöhnliche Wassermelone, Wasserzitrulle. VIETNAMESE : Dưa hấu, Dưa hấu ruột đỏ.

Botany
Pakuan is a spreading, hairy, tendril-bearing annual vine reaching a length of several meters. Leaves are long-stalked, oblong-ovate, 8 to 20 centimeters long, deeply 3- to 7-lobed, pinnatifid with usually narrowed segments. Flowers are monoecious, yellow, and about 2 centimeters in diameter, occurring singly in axils of the leaves. Fruit is very large, smooth, ellipsoid to oblong, light green with irregular dark green-mottled stripes, sometimes covered with a white, waxy bloom, about 30 centimeters long. The flesh is white, yellowish, pink or red; crisp, soft and juicy. Seeds are compressed, sometimes red, usually black.

Pakuan

Distribution
– Widely cultivated in the Philippines.

Pakuan2

Constituents
– Fruit extract yielded carbohydrates, proteins, amino acids, steroids, glycosides, flavonoids, tannins and polyphenols.
– The skin contains a fixed oil, arachidic acid, and traces of copper.
The seeds contain oil, 15 to 45%, made up of glycerides of linoleic acid, oleic acid and palmitic and stearic acids. The oil contains a small amount of phytosterol.
– A study suggests the active principle in the seed is a glucoside-saponin named cucurbocitrin.
– Flesh of fruit contains saccharose, dextrose, levulose, invert sugar, citrullin, lycopin, carotin, etc.
– All parts of the watermelon – rind, flesh, and seeds – contain citrulline, a non-essential amino acid, which converts to L-arginine when eaten.
– Seeds are a rich source of enzyme urease.
– Unsaturated fatty acid content of an ether extract in water melon seeds was reported at 76.1%, mainly linoleic acid.
– Study of vine yielded ten compounds: pentadecanoic acid, monopentadecanoin, 2, 3-dihydroxypropyl nonadecoate, lignoceric acid-2, 3-dihydroxy-propanenyl ester, lancerebroside 5, salicylic acid, 4-hydroxybenzoic acid, hydroquinone, succinic acid and vanillic acid.
– Alcoholic and aqueous extracts revealed the presence of carbohydrates, proteins, flavonoids, saponins, fixed oils, glycosides and steroids.

Additional Sources and Suggested Readings

(1) Protective role of Mangifera indica, Cucumis melo and Citrullus vulgaris peel extracts in chemically induced hypothyroidism / Chemico-Biological Interactions Vol 177, Issue 3, 12 February 2009, Pages 254-258

(2) Free Amino Acids in Citrullus vulgaris (Watermelon) / PEDIATRICS Vol. 73 No. 6 June 1984, pp. 879

(3) Elevated plasma citrulline and arginine due to consumption of Citrullus vulgaris (watermelon) 

(4) Mosquitocidal and repellent activity of the leaf extract of Citrullus vulgaris (cucurbitaceae) against the malarial vector, Anopheles stephensi liston (diptera culicidae) / K Mullai et al / Eur Rev Med Pharmacol Sci 2008; 12 (1) : 1-7

(5) Determination of citrulline in watermelon rind / Agnes M. Rimando, Penelope M. Perkins-Veazie / Journal of Chromatography A, Volume 1078, Issues 1–2, 17 June 2005, Pages 196–200

(6) Is Watermelon A Natural Viagra? / Karthleen Doheny, July 2007 / Web MD

(7) Want Citrulline? Try Watermelon / Aug 2007 / Science Daily

(8) ARE WATERMELON SEEDS RICH IN CITRULLINE? / Suzanne Robin / LiveSTRONG

(9) Effects of Watermelon Supplementation on Aortic Blood Pressure and Wave Reflection in Individuals With Prehypertension: A Pilot Study / Arturo Figueroa, Marcos A. Sanchez-Gonzalez, Penelope M. Perkins-Veazie and Bahram H. Arjmandi / 2010 American Journal of Hypertension

(10) Sorting Ctrullus names / Maintained by: Michel H. Porcher, / MULTILINGUAL MULTISCRIPT PLANT NAME DATABASE

(11) Studies on urease from the seeds of Citrullus vulgaris: action of chemical agents and ionizing radiations / Hargreaves AB, Marcondes N, Elias CA. / An Acad Bras Cienc. 1976;48(3):567-76.

(12) Water melons (Citrullus vulgaris) as the main source of water for cattle in central Tanzania / C.M. SHAYO, B. OGLE and P. UDÉN / Tropical Grasslands (1996) Volume 30, 308–313 308

(13) Screening of Anti-microbial Effect in Watermelon (Citrullus sp.) / P. Thirunavukkarasu, T. Ramanathan, N. Ravichandran and L. Ramkumar / Journal of Biological Sciences, 10: 682-685.

(14) Study on chemical constituents of Citrullus vulgaris Schrad vine (II) / Gong XM, Wang S, Zhou XL, Zhou DD, Dai H, Deng JG. / Zhong Yao Cai. 2013 Oct;36(10):1614-6.

(15) Anti-diabetic effect of watermelon (Citrullus vulgaris Schrad) on Streptozotocin-induced diabetic mice / Jiyun Ahn, Wonhee Choi, Suna Kim, Taeyoul Ha / Food Science and Biotechnology, February 2011, Volume 20, Issue 1, pp 251-254

(16) Corrosion Protection of Zinc in Natural Sea Water using Citrullus Vulgaris peel as an Inhibitor / Petchiammal A., Deepa Rani P., Selvaraj S. and Kalirajan K. / Research Journal of Chemical Sciences, Vol. 2(4), 24-34, April (2012)

Pakuan4Pakuan3

Properties
– Seeds considered cooling, demulcent, diuretic, vermifuge, nutritive, pectoral and pectic.
– The crude extract of seeds believed to have a lowering blood pressure effect.

Parts utilized 
Seeds, roots.

Uses
Edibility / Nutrition
Widely eaten in the Philippines.
Not high in nutritive value; only a fair source of calcium and iron.
Seeds are oily; sometimes used as substitute for peanuts.

Folkloric
– The juice of the roots used for hemorrhage after abortion.
– Juice of fruit use as antiseptic in typhus fever.
– With cumin and sugar, juice is used as a cooling drink in strangury and affections of the urinary organs, such as gonorrhea; also used for hepatic congestion and intestinal catarrh.
– In China, rind of the fruit is powdered after drying and incineration and used for aphthous mouth sores.
– Pulp is used as a drastic purgative.
– In Tonkin, pericarp used for diarrhea.
– Seeds used to alleviate symptoms of acute cystitis.
– In traditional Chinese medicine, used to relieve scanty urination, excessive thirst, for treating icteric hepatitis and urinary tract infections.

Wassermelone / Citrullus lanatus Crimson Oval

Others
– Water source / Alternative Food Source: In the semi-arid central Tanzania, water melons are available in appreciable quantities to be used as livestock as water source during the dry season. One hectare can produce sufficient water melons to supply water to a growing bull for 3-5 months. In years of famine, the rind is dried and made into porridge. Farmers also extract oil from the melon seeds to use for cooking.

Study Findings
• Hypothyroidism: Protective role of Mangifera indica, Cucumis melo and Citrullus vulgaris peel extracts in chemically induced hypothyroidism: Results showed thyroid stimulatory and antiperoxidase roles.
• Mosquitocidal / Repellent: Mosquitocidal and repellent activity of the leaf extract of Citrullus vulgaris (cucurbitaceae) against the malarial vector, Anopheles stephensi liston (diptera culicidae): The C vulgaris plant showed insect growth regulatory activity against Anopheles stephensi.
• Thyroid Stimulation / Regulation of Lipid Peroxidation: Study of the fruit peel extracts of M indica, C melo and Citrullus vulgaris showed stimulatory thyroid activity in PTU-induced hypothyroid animals and lipid peroxidation inhibition. but only when treated individually. A parallel increase in hepatic and renal LPO was observed when used in combination.
• Citrulline / Rind: Watermelon is a natural and rich source of the non-essential amino acid citrulline. It is used in the nitric oxide system, with potential antioxidant and vasodilatory effects. Red flesh watermelons had slightly less citruline than yellow or orange flesh watermelons. Rind contains more citrulline than flesh. The watermelon rind, an underutilized agricultural waste, presents as a rich source of natural citrulline.
• Supplementation / Improved Aortic Blood Pressure: Study showed watermelon supplementation improves aortic hemodynamics through a decrease in the amplitude of the reflected wave in individuals with prehypertension. Supplementation was well tolerated by all subjects, with no adverse effects reported.
• Antioxidant: Of eleven fruits studied, C. vulgaris was next to Phyllanthus emblica in total antioxidant capacity.
• Antimicrobial: Study showed the leaves extract of C. colocynthis, C. lanatus and C. vulgaris were very effective against bacteria and some fungal strains than other species. All three showed maximum inhibition against E. coli and Candida albicans.
• Anti-Diabetic Effect: Study evaluated the anti-diabetic potential of various extracts of watermelon in vivo in streptozotocin induced diabetic mice. Results showed significant reduction of blood glucose levels, increased insulin levels, and protection from pancreatic cell death. Results showed beneficial antidiabetic effects.
• Corrosion Inhibitor / Peels: Study showed Citrillus vulgaris peels can serve as effective inhibitor on zinc in natural sea water environment. Results suggest the adsorption of inhibitor on zinc metal surface is exothermic and followed by spontaneous process.
• Anti-Obesity / Anti-Arthritic / Seeds: Study evaluated the anti=obesity and anti-arthritic activities of seed extracts of C. vulgaris in rat models. The extracts exhibited significant anti-obesity activity with reduction of glucose, cholesterol, LDL, VLDL, triglycerides, with increase in HDL in induced obesity models in rats, with Sibutramine as standard reference. Extracts also showed significant anti-arthritic activity in FA induced arthritis in rat models.

In the news
Citrulline / Natural Viagra®: The fruit is rich in the amino acid citrulline, which is converted to the amino acid arginine (L-arginine is the precursor for endothelial nitric oxide synthesis), which is known to relax and dilate blood vessels, an effect similar to Viagra and other drugs used to treat erectile dysfunction. A 4-ounce serving of watermelon (about 10 watermelon balls) provides about 150 milligrams of citrulline. A 2007 study of volunteers who drank three 8-ounce glasses of watermelon juice daily for three weeks boosted their arginine levels by 11%. However, like many herbs and fruits touted as herbal viagra, the citrulline-viagra connect is short on science. Men with erectile dysfunction are not deficient in arginine. Still, alternative practitioners recommend citrulline for the treatment of impotence. The normal supplemental dose is 16 to 18 g of citrulline malate.

Caution !
• Watermelon-induced citrullinemia and urea cycle disorders: Elevated plasma citrulline and arginine due to consumption of Citrullus vulgaris (watermelon): A Case of a 19-month old with developmental delay who developed watermelon-induced citrullinemia. Its laboratory hallmarks are elevation of plasma citrulline and moderate elevation of plasma arginine.
• While high levels of citrulline might not affect most people, it can be harmful to those with citrullinemia, a genetic disorder affecting the urea cycle.
• Current dietary management of citrullinemia and other urea cycle disorders include restriction of protein, sodium benzoate, and certain dietary supplements or essential amino acids with intermediates such as arginine. One fruit that should be avoided is watermelon (Citrullus vulgaris).

Availability
– Cultivated.
– Citrulline supplements.