Family • Magnoliceae - Michelia alba DC. - WHITE CHAMPAKA - Bai yu lan
|Michelia alba DC.|
|Banana shrub (Engl.)|
|White champaca (Engl.)|
|Bai yu lan (Chin.)|
Additional Sources and Suggested Readings
(1) (−)-N-Formylanonaine from Michelia alba as a human tyrosinase inhibitor and antioxidant / Hui-Min Wang, Chung-Yi Chen et al / Bioorganic & Medicinal Chemistry, Vol 18, Issue 14, 15 July 2010, Pages 5241-5247 / doi:10.1016/j.bmc.2010.05.045 |
(2) Antimicrobial Activity of Essential Oils Against Five Strains of Propionibacterium acnes / S Luangnarumitchai et al / Mahidol University Journal of Pharmaceutical Sciences 2007; 34(1-4): 60-64.
(3) A Preliminary Study on the Chemical Constituents of the Essential Oil of Michelia alba Dc. / Zhu Liang-feng, Lu Bi-yao and Xu Dan / Acta Botanica Sinica Volume 24 Issue 4 / Journ of Integrative Plant Biology
(4) Inhibitory effects of Michelia alba on matrix metalloproteinases expression: Application in preventing photoaging / Kuo-Ching Wen et al / AGFD 150
(5) Experimental Study on Antiasthmatic Action of Kechuanbiwenan(Flower of Michelia Alba DC ,Herba Ephedrac) / Luo Qifu / DOI: CNKI:SUN:ZCYA.0.1995-03-016
– Volatile oil, 0.0125% – linalool, methyl eugenol, methy ethyl– acetic ester, acetic acid.
– Study isolated ten compounds from the leaves: (-)-N-formylanonaine, (-)-oliveroline, (+)-nornuciferine, lysicamine, (+)-cyperone, (+)-epi-yangambin, ficaprenol-10, pheophytin a, aristophyll C and michephyll A.
– Infusion of flowers used as vaginal wash.
– Perfume: Essential oil from flowers used in perfumery; also for tea-perfuming.
• Antioxidant / Human Tyrosinase Inhibitor: Tyrosinase is the first and rate limiting enzyme in the synthesis of melanin pigments for coloring of the hair, skin and eyes. Study yielded a natural product, (-)-N-formylanonaine, from the leaves of Michelia alba. The compound exhibited antioxidant activities and showed tyrosinase and melanin reducing activities in human epidermal melanocytes without apparent toxicity to human cells.
• Phytochemicals / Antioxidant / Michephyll A: Study yielded 10 compounds from the leaves, including michephyll A, a new compound with antioxidant activity.
• Antibacterial: Study of 22 essential oils fro Thai medicinal plants against 5 strains of Propionibacterium acnes showed 19 with inhibitory activity on P acnes growth, and four, including michelia oil, with the strongest antibacterial activity. The essential oils suggest a possible alternative treatment for acne.
• Essential Oil Constituents: Essential oil yielded 24 constituents: campbene, β-pinene, α-phellandrene, β-myrcene, limonene, 1,8-cineole, ocimene, 3-carene, o-cymene, α-cubebene, trans-linalool oxide, β-cubebene, linalool, cis-caryophyllene, β-selin- erie, trans-carveol, methyl, eugenol, β-bisabolene, methyl isoeugenol, isoaristolene, among others.
• Photoaging Prevention: UV radiation from the sun can cause skin photoaging by inducing matrix metalloproteinases (MMPs). Study investigated M. alba’s polyphenols for protective activity. Results showed MA treatment may prevent UVB-induced extracellular matrix damage by inhibiting the expression of MMP-1 and MMP-3.
• Antiasthmatic: Study on guinea-pig showed that MA flowers can antagonize tracheal spasm induced by histamine or acetylcholine, increase perfusion flow and prolong the incubation period of induced asthma and relax asthma symptoms.
• Cytotoxic Constituents: Study of methanol extract of leaves of M. alba yielded one new chlorophyll, michephyll A (a novel furanone) and 28 known compounds. (-)-anonaine was the major constituent and showed cytotoxicity against HeLa cells.
Leaf essential oil and flower oil in the cybermarket.